Internet poker rooms are highly profitable ventures
for their owners, and any large, well-established
room should be perfectly safe. As of this writing,
the fastest way to see which rooms are the largest
is to visit PokerPulse.com, which tracks the number
of games and players at leading sites.
This doesn't mean you should necessarily rule out
a newer or smaller Internet poker room from consideration,
but unless it is owned by people of substantial means,
and/ or has people of high established integrity and
fame committing their names and assets to it, you're
probably better off waiting a little while to see
how the new room performs.